Comparison between platelet-rich plasma and autologous iliac grafts for tibial osteotomy

This report has been verified by one or more authors of the original publication.

25 patients with varus deformity undergoing medial opening wedge high tibial osteotomy of the knee were randomized to determine the efficacy of platelet-rich plasma (PRP) combined with a biological graft of bone marrow aspirate compared to an autologous iliac graft. Participants were allocated to receive either the biological graft, or the gold-standard autologous iliac bone graft, and were followed-up for 24 weeks postoperatively. Kaplan-Meier estimates indicated that bone healing took longer in those who received the PRP graft, but the difference between groups was not significant. By the end of the 24-week study period, consolidation was observed in 10 of the 11 patients who received the biological graft compared to all patients who were treated with the iliac bone graft.