Three meta-analyses with overlapping studies were included in this review comparing outcomes after anterior cruciate ligament (ACL) reconstruction with bioabsorbable versus metallic interference screws. Between 8 and 11 studies were included in each meta-analysis, and performed analyses on outcomes such as the Lysholm score, International Knee Documentation Committee (IKDC) score, Tegner score, KT-arthrometer results, pivot-shift test, radiological examination of tunnel widening, and postoperative complications. All three included studies reported no significant differences in clinical or functional outcome measures. There was, however, a higher rate of complications noted with bioabsorbable interference screw fixation, such as knee effusion, femoral tunnel widening, and screw breakage.