Aspirin reduces risk of recurrence in patients with unprovoked venous thromboembolism .
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Aspirin for preventing the recurrence of venous thromboembolism
N Engl J Med. 2012 May 24;366(21):1959-67. doi: 10.1056/NEJMoa1114238Two weeks following the completion of treatment with vitamin K antagonists, 403 patients with a previous unprovoked venous thromboembolism (VTE) were randomised into two groups. Patients either received 100 mg aspirin or a placebo, once per day for 2 years, to measure the recurrence of VTE. Following assessments every 3 months in the first year and every 6 months in the second year, the results demonstrated that aspirin, taken after anticoagulant treatment, was effective in preventing recurrence of unprovoked VTE.
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