Analysis of efficacy of different hyaluronic acid products in treatment of knee OA .
Hyaluronic acid in the treatment of knee osteoarthritis: a systematic review and meta-analysis with emphasis on the efficacy of different products
BioDrugs. 2012 Aug 1;26(4):257-6874 trials evaluating the efficacy of hyaluronic acid products in the treatment of knee osteoarthritis were included in the current meta-analysis. The purpose of this study was to examine results associated with pain relief at 3 months for hyaluronic acid products and placebo. Meta-analysis demonstrated a significantly lower pain by 10.20mm on a visual analog scale for hyaluronic acid groups, overall, compared to placebo, though a unit-of-analysis error was present. Subgroup analysis of different HA products versus placebo demonstrated variable effects sizes, though no consistent, statistically significant benefit across products.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
