Addition of low-dose morphine to spinal anaesthesia improves analgesia with cFNB in TKA .
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Comparison of continuous femoral nerve block (CFNB/SA) and continuous femoral nerve block with mini-dose spinal morphine (CFNB/SAMO) for postoperative analgesia after total knee arthroplasty (TKA): a randomized controlled study
BMC Anesthesiol. 2016 Jul 16;16(1):3870 patients scheduled for total knee arthroplasty under spinal anesthesia and a continuous femoral nerve block were randomized to spinal anesthesia with or without the addition of mini-dose morphine (0.035mg). The purpose of this study was to evaluate if there was any significant difference between groups in pain scores and opioid consumption. Patients were monitored up to 48 hours postoperatively. Results demonstrated significantly lower pain scores and tramadol consumption in the group which received mini-dose spinal morphine. The incidence of postoperative nausea and vomiting was significantly greater within the first 6 hours in the group administered the mini-dose spinal morphine.
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