Forty patients who underwent a total knee arthroplasty (TKA) for end-stage knee osteoarthritis (OA) were randomized to receive continuous passive motion (CPM) combined with manual standard therapy (n=20) or manual standard therapy alone (n=20) after TKA surgery. The outcomes of interest included the following: passive range of movement (PROM), the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), the functional section of the Knee Society Score (KSS), range of motion in flexion, and extension deficit. The WOMAC and KSS scores were measured at 2-years follow-up whereas all other outcomes were measured at 2-years follow-up and at time of discharge. Results revealed that none of the outcomes were statistically significantly different between the CPM and control groups at 2-years follow-up (p>0.05 for all), however, flexion and PROM at time of discharge were found to be statistically significantly higher in the CPM group (p=0.04, and p=0.02; respectively).