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Previous Ace Report AAOS2018: IV TXA reduced blood loss in total shoulder arthroplasty Next Ace Report AAOS2018: No difference in analgesic efficacy of single-shot versus continuous ACB in TKA
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Osteoarthritis
AAOS2018: TissueGene-C demonstrates 52-week efficacy versus placebo in treatment of moderate knee OA
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AAOS2018: TissueGene-C demonstrates 52-week efficacy versus placebo in treatment of moderate knee OA .

TissueGene-C (TG-C), a Novel Cell and Gene Therapy for the Treatment of Osteoarthritis

Contributing Authors

MC Lee JH Lee CH Choi Y In J Yoo S Bin SD Cho CW Ha HS Kyung MG Kim E Choi HJ Ku

163 patients with Kellgren-Lawrence grade III knee osteoarthritis were randomized to intraarticular treatment with either TissueGene-C or placebo. Patients were assessed for outcome on clinical scores, including the International Knee Documentation Committee (IKDC) score, a visual analog scale, and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), over 52-week follow-up. Results for all three clinical scores significantly favoured the TissueGene-C group compared to placebo group after 52 weeks.

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OrthoEvidence. AAOS2018: TissueGene-C demonstrates 52-week efficacy versus placebo in treatment of moderate knee OA. ACE Report. 2018;7(4):8. Available from: https://myorthoevidence.com/AceReport/Show/aaos2018-tissuegene-c-demonstrates-52-week-efficacy-versus-placebo-in-treatment-of-moderate-knee-oa

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