Thumb carpometacarpal osteoarthritis: Radial nerve mobilization as a possible treatment .
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OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2013;1(14):8 Arch Phys Med Rehabil. 2012 Mar;93(3):396-403. doi: 10.1016/j.apmr.2011.08.045. Epub 2012 Jan 260 patients with dominant-hand thumb carpometacarpal osteoarthritis (OA) were randomized into two groups to measure the effects of either radial nerve mobilization treatment or a nontherapeutic placebo treatment on pain sensitivity and pinch strength. At 2 months follow-up, patients who underwent radial nerve mobilization experienced a decrease in pain sensitivity in the trapeziometacarpal joint and an increase in tip and tripod pinch strength.
Was the allocation sequence adequately generated?
Was allocation adequately concealed?
Blinding Treatment Providers: Was knowledge of the allocated interventions adequately prevented?
Blinding Outcome Assessors: Was knowledge of the allocated interventions adequately prevented?
Blinding Patients: Was knowledge of the allocated interventions adequately prevented?
Was loss to follow-up (missing outcome data) infrequent?
Are reports of the study free of suggestion of selective outcome reporting?
Were outcomes objective, patient-important and assessed in a manner to limit bias (ie. duplicate assessors, Independent assessors)?
Was the sample size sufficiently large to assure a balance of prognosis and sufficiently large number of outcome events?
Was investigator expertise/experience with both treatment and control techniques likely the same (ie.were criteria for surgeon participation/expertise provided)?
Ja = 1
Ungewiss = 0.5
Nicht relevant = 0
Nein = 0
Die Bewertung der Berichtskriterien bewertet die Transparenz, mit der die Autoren die methodischen und studienspezifischen Merkmale der Studie in der Veröffentlichung angeben. Die Bewertung ist in fünf Kategorien unterteilt, die im Folgenden vorgestellt werden.
4/4
Randomization
4/4
Outcome Measurements
4/4
Inclusion / Exclusion
4/4
Therapy Description
3/4
Statistics
Detsky AS, Naylor CD, O'Rourke K, McGeer AJ, L'Abbé KA. J Clin Epidemiol. 1992;45:255-65
Der Fragilitätsindex ist ein Instrument, das bei der Interpretation signifikanter Ergebnisse hilft und ein Maß für die Stärke eines Ergebnisses liefert. Der Fragilitätsindex gibt die Anzahl der aufeinanderfolgenden Ereignisse an, die zu einem dichotomen Ergebnis hinzugefügt werden müssen, damit das Ergebnis nicht mehr signifikant ist. Eine kleine Zahl steht für ein schwächeres Ergebnis und eine große Zahl für ein stärkeres Ergebnis.
Warum wurde diese Studie jetzt benötigt?
Thumb carpometacarpal OA affects many people, especially women, in Europe and the United States. The cause of this upper limb-related disability is a result of the modification of the trapeziometacarpal joint. Consequently, those with the condition have difficulty with pinch and grip strength and experience much pain. Thumb carpometacarpal OA may be treated by undergoing surgery, but it only results in partial improvement. Neurodynamic techniques have been suggested as additional treatments on top of surgery in managing pain and improving pinch strength, but not many studies have tested the outcomes of applying such methods. Hence, this study aimed to test the efficacy of the neurodynamic technique, radial nerve mobilization, in treating thumb carpometacarpal OA.
Was war die wichtigste Forschungsfrage?
Did radial nerve mobilization treatment for dominant-hand thumb carpometacarpal OA decrease pain sensitivity in the thumb and increase pinch strength, when measured over a 2 month period?
- PP-There was a significant improvement in PPT of the trapeziometacarpal joint between all assessments for the Radial Nerve Mobilization group (p<0.001), but not for the placebo group.
- There were significant improvements in PPT of the scaphoid and hamate bones between the first and second months of assessments for both groups, but no significant difference between groups (p=0.06).
- There was a significant difference in tip and tripod pinch strength between pre-treatment and post-treatment assessments for the Radial Nerve Mobilization group (p=0.04).
- There were no significant differences in tip and tripod pinch strength during assessments at 1 and 2 months following treatment between the Radial Nerve Mobilization group and the placebo group (p>0.05).T and pinch strength were measured prior to and 5 minutes, 1, and 2 months following to treatment.
Was sollte ich mir besonders merken?
The results displayed that radial nerve mobilization treatment of dominant-hand thumb carpometacarpal OA was effective in increasing mechanical pain sensitivity in the trapeziometacarpal joint and increasing tip and tripod pinch strength.
Wie wird sich dies auf die Behandlung meiner Patienten auswirken?
Radial nerve mobilization was successful when focussing on its effects on neurophysiological function of patients. However, it is uncertain whether improvements would be observed if pain or disability scales for the hand were used instead. Future studies should incorporate these scales to measure outcomes and a larger sample size should be included.
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