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Exercise and ultrasonography are effective in treating adults with knee osteoarthritis
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OSTEOARTHRITIS
Exercise and ultrasonography are effective in treating adults with knee osteoarthritis .
Verified
This report has been verified by one or more authors of the original publication.
High Impact
Este estudio ha sido identificado como potencialmente de alto impacto. La métrica de alto impacto de OE, impulsada por la IA, estima la influencia que probablemente tendrá un artículo integrando señales tanto de la revista en la que se publica como del contenido científico del propio artículo. Desarrollado mediante el procesamiento del lenguaje natural más avanzado, el modelo de Alto Impacto de OE predice con mayor precisión el futuro rendimiento de las citas de un estudio que el factor de impacto de la revista por sí solo. Esto permite reconocer antes las investigaciones clínicamente significativas y ayuda a los lectores a centrarse en los artículos con más probabilidades de configurar la práctica futura.

OrthoEvidence Journal (OE Journal) - ACE Report

OE Journal. 2013;1(11):177 Ann Intern Med. 2012 Nov 6;157(9):632-44. doi: 10.7326/0003-4819-157-9-201211060-00007

This meta-analysis and systematic review included 193 studies (84 randomized controlled trials were assessed in the meta-analysis) comparing physical therapy to a control group in patients with knee osteoarthritis (OA). The most effective interventions were ultrasonography, and aerobic, aquatic, strengthening, and proprioception exercise. Education, orthotics, taping, tai chi, and pulsed electromagnetic fields had no clinically significant effect on any of the patient-centered or functional outcomes of interest. Few adverse events occurred in the studies.


Detalles de la financiación de la publicación +
Financiación:
Non-Industry funded
Patrocinador:
AHRQ
Conflictos:
Other

Riesgo de sesgo

9,5/10

Criterios de información

19/20

Índice de fragilidad

N/A

Were the search methods used to find evidence (original research) on the primary question or questions stated?

Was the search for evidence reasonably comprehensive?

Were the criteria used for deciding which studies to include in the overview reported?

Was the bias in the selection of studies avoided?

Were the criteria used for assessing the validity of the included studies reported?

Was the validity of all of the studies referred to in the text assessed with use of appropriate criteria (either in selecting the studies for inclusion or in analyzing the studies that were cited)?

Were the methods used to combine the findings of the relevant studies (to reach a conclusion) reported?

Were the findings of the relevant studies combined appropriately relative to the primary question that the overview addresses?

Were the conclusions made by the author or authors supported by the data and or analysis reported in the overview?

How would you rate the scientific quality of this evidence?

Sí = 1

Incierto = 0,5

No relevante = 0

No = 0

La evaluación de los criterios de información evalúa la transparencia con la que los autores informan de las características metodológicas y del ensayo dentro de la publicación. La evaluación se divide en cinco categorías que se presentan a continuación.

4/4

Introduction

4/4

Accessing Data

4/4

Analysing Data

4/4

Results

3/4

Discussion

Detsky AS, Naylor CD, O'Rourke K, McGeer AJ, L'Abbé KA. J Clin Epidemiol. 1992;45:255-65

El Índice de Fragilidad es una herramienta que ayuda en la interpretación de hallazgos significativos, proporcionando una medida de fuerza para un resultado. El Índice de Fragilidad representa el número de eventos consecutivos que es necesario añadir a un resultado dicotómico para que el hallazgo deje de ser significativo. Un número pequeño representa un hallazgo más débil y un número grande un hallazgo más fuerte.

¿Por qué se necesitaba ahora este estudio?

Although osteoarthritis (OA) is already one of the foremost causes of disability among noninstitutionalized adults today, its prevalence continues to increase as the population ages. Nonsurgical treatments for OA such as physical therapy are prescribed in the hopes of reducing pain and disability, and improving function and quality of life. This meta-analysis and systematic review aimed to be the first to evaluate the effectiveness of different exercise types and nonsurgical interventions in order to determine which physical therapy treatments are best for patients with osteoarthritis of the knee.

¿Cuál era la pregunta principal de la investigación?

Is physical therapy more effective than a control treatment with respect to patient-centered outcomes, function, and complications in patients with osteoarthritis of the knee?

Características del estudio +
Fuente de datos:
A search was conducted for articles from 1970 to February 29, 2012 using MEDLINE, the Cochrane Library, the Physiotherapy Evidence Database, Scirus, Allied and Complementary Medicine, and the Health and Psychosocial Instruments bibliography database. The reference lists from systematic reviews and eligible studies were searched manually. A search of ClinicalTrials.gov was also done, and sponsors of ongoing trials were contacted for more information.
Términos del índice:
The following Medical Subject Headings (MeSH) terms and text words were used: osteoarthritis knee, physical therapy modalities, pain measurement, activities of daily living, quality of life.
Selección de estudios:
Studies included were English randomized controlled trials comparing physical therapy to a sham treatment, usual care, or no treatment in adult patients with knee OA. Outcomes of interest were pain, disability, quality of life, perceived health status, global effectiveness, gait function, strength, transfers, joint function, and composite function. Nonrandomized clinical trials, case series, and observational cohort or case-control studies were also included to assess adverse events. Eligibility was determined by at least 2 investigators.
Extracción de datos:
One reviewer extracted the data and second assessed the accuracy of the data. Disagreements were documented, resolved through discussion.
Síntesis de datos:
Stata was used to compile the data from 84 of the randomized controlled trials. Continuous outcomes were expressed as standardized mean differences (SMD). Statistical heterogeneity was calculated with the chi squared and I2 test. Random effects models were used for the analysis.
¿Cuáles fueron los hallazgos importantes?
  • Education, orthotics, taping, tai chi, and pulsed electromagnetic fields had no clinically significant effect on any of the outcomes of interest
  • There was a significant reduction in pain when patients received proprioception exercise (4 studies; SMD, -0.71 [95% CI, -1.31 to 0.11]) or diathermy (5 studies; significant at 1 month only; SMD, -0.53 [CI, -0.96 to -0.10]); the two interventions did not demonstrate significant effects for any other outcomes
  • Massage led to a significant improvement in composite function (3 studies; SMD, -0.55 [CI, -0.93 to -0.18])
  • Aquatic exercise resulted in significantly reduced disability (3 studies; SMD, -0.28 [CI, -0.51 to -0.05])
  • According to 11 studies, aerobic exercise significantly reduced long term pain (SMD, -0.21 [CI, -0.35 to -0.08]; this was not clinically significant), disability (SMD, -0.21 [CI, -0.37 to -0.04]), composite function within 3 months (WOMAC function score -15.4 [CI -24.8 to -5.92]), and gait function over 12 months (walking speed difference -0.11 m/s [CI, -0.17 to -0.05])
  • Results from 9 studies demonstrated that strengthening exercise resulted in clinically significant reduction in pain (SMD, 0.68 [CI, -1.23 to -0.14]) and improvement in composite function (SMD, -1.00 [CI, -1.95 to 0.05])
  • electrical stimulation significantly improved global assessment scores in two studies and muscle strength at 3 months in two studies (values not provided)
  • According to 6 studies, ultrasonography led to clinically significant improvement in pain (SMD, -0.74 [CI, 0.95 to -0.53]), composite function (SMD, -1.14 [CI, 1.85 to -0.42]), and gait function (SMD, -1.48 [CI, 2.08 to -0.89])
¿Qué es lo que más debo recordar?

Aerobic, aquatic, strengthening, and proprioception exercise, as well as ultrasonography were shown to be effective in improving patient-centered outcomes and/or function.

¿Cómo afectará esto al cuidado de mis pacientes?

This study demonstrated with low-strength evidence that aerobic and aquatic exercise improved disability and that aerobic exercise, strengthening exercise, and ultrasonography reduced pain and improved function. However, further investigation is required based on the limited evidence for individualized treatment decisions.

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OrthoEvidence. Exercise and ultrasonography are effective in treating adults with knee osteoarthritis. OE Journal. 2013;1(11):177. Available from: https://myorthoevidence.com/AceReport/Show/

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