TKA: Similar pain outcomes for local infiltration anesthesia and continuous femoral block .
OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2013;1(11):33 Acta Orthop. 2011 Aug;82(4):441-7. Epub 2011 May 1140 patients undergoing total knee arthroplasty with spinal anaesthesia were randomized to receive either a local infiltration of anaesthesia or a continuous femoral block. The primary outcome was pain at rest and at movement. The results at 24 hours postoperatively indicated both interventions produced comparable analgesic effect. Local infiltration of anaesthesia may be preferred, because it is more cost-effective and easier to execute.
Was the allocation sequence adequately generated?
Was allocation adequately concealed?
Blinding Treatment Providers: Was knowledge of the allocated interventions adequately prevented?
Blinding Outcome Assessors: Was knowledge of the allocated interventions adequately prevented?
Blinding Patients: Was knowledge of the allocated interventions adequately prevented?
Was loss to follow-up (missing outcome data) infrequent?
Are reports of the study free of suggestion of selective outcome reporting?
Were outcomes objective, patient-important and assessed in a manner to limit bias (ie. duplicate assessors, Independent assessors)?
Was the sample size sufficiently large to assure a balance of prognosis and sufficiently large number of outcome events?
Was investigator expertise/experience with both treatment and control techniques likely the same (ie.were criteria for surgeon participation/expertise provided)?
Sì = 1
Incerto = 0,5
Non rilevante = 0
No = 0
La valutazione dei criteri di segnalazione valuta la trasparenza con cui gli autori riportano le caratteristiche metodologiche e sperimentali dello studio all'interno della pubblicazione. La valutazione è suddivisa in cinque categorie che vengono presentate di seguito.
4/4
Randomization
2/4
Outcome Measurements
2/4
Inclusion / Exclusion
4/4
Therapy Description
4/4
Statistics
Detsky AS, Naylor CD, O'Rourke K, McGeer AJ, L'Abbé KA. J Clin Epidemiol. 1992;45:255-65
L'Indice di Fragilità è uno strumento che aiuta l'interpretazione dei risultati significativi, fornendo una misura della forza di un risultato. L'Indice di Fragilità rappresenta il numero di eventi consecutivi che devono essere aggiunti a un risultato dicotomico per rendere il risultato non più significativo. Un numero piccolo rappresenta un risultato più debole, mentre un numero grande rappresenta un risultato più forte.
Perché questo studio era necessario ora?
Total knee arthroplasty (TKA) can produce severe postoperative pain, which may delay recovery. There are a number of pain treatments present, such as femoral nerve block or epidural analgesia. Local infiltration analgesia (LIA) has become a popular choice in pain management, but its effectiveness has yet to be fully evaluated. This study examines the outcomes of pain when patients undergoing total knee arthroplasty receive either a local infiltration of anaesthesia or a continuous femoral block.
Qual era la domanda di ricerca principale?
What are the outcomes in pain with an intervention involving a peri- and intra-articular infiltration of anesthesia or a continuous femoral block in patients undergoing total knee arthroplasty at 24 hours postoperatively?
- The local infiltration anaesthesia group (Group LIA) reported lower average pain at rest compared to the femoral nerve block group. (Group F) (Group LIA: 1.6, Group F: 2.2)
- 7/19 patients in Group F reported a pain intensity of >7 upon movement compared to only 1/20 patients in Group LIA. (p=0.04, Fisher's exact test)
- Both groups indicated comparable consumption of morphine per kg. (Femoral block: 0.4 (0.3-0.5) mg/kg; LIA: 0.3 (0.2-0.4) mg/kg)
- No adverse events were reported within the 24 hour postoperative study period.
Che cosa devo ricordare di più?
Both the local infiltration anaesthesia intervention and the femoral nerve block interventions provided good analgesic effect in patients after total knee arthroplasty. However, local infiltration anaesthesia may be a preferred option, because of its cost-effectiveness and ease of administration compared to the femoral nerve block.
Come influenzerà l'assistenza ai miei pazienti?
Both local infiltration anaesthesia and femoral nerve block described in this study provide good analgesia following TKA. However, local infiltration anaesthesia may be a preferred treatment due to lower costs and the ease to perform this technique.
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