Early surgery in sciatica patients results in improved pain relief and perceived recovery .
This report has been verified
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OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2013;1(11):249 N Engl J Med. 2007 May 31;356(22):2245-56Exclusive Author Interview
Dr. Wilco Peul discusses early surgery versus prolonged conservative treatment for sciatica.
283 patients with disc herniation and resulting sciatica were randomized to either receive early surgery or prolonged conservative treatment for 6 months (followed by surgery if needed). The results indicated that for both groups, similar outcomes were observed at the one year follow up period. However it is important to note that those in the early surgery group demonstrated faster rate of pain relief and perceived recovery, and thus may render this treatment method a valid and supported option.
Was the allocation sequence adequately generated?
Was allocation adequately concealed?
Blinding Treatment Providers: Was knowledge of the allocated interventions adequately prevented?
Blinding Outcome Assessors: Was knowledge of the allocated interventions adequately prevented?
Blinding Patients: Was knowledge of the allocated interventions adequately prevented?
Was loss to follow-up (missing outcome data) infrequent?
Are reports of the study free of suggestion of selective outcome reporting?
Were outcomes objective, patient-important and assessed in a manner to limit bias (ie. duplicate assessors, Independent assessors)?
Was the sample size sufficiently large to assure a balance of prognosis and sufficiently large number of outcome events?
Was investigator expertise/experience with both treatment and control techniques likely the same (ie.were criteria for surgeon participation/expertise provided)?
Sí = 1
Incierto = 0,5
No relevante = 0
No = 0
La evaluación de los criterios de información evalúa la transparencia con la que los autores informan de las características metodológicas y del ensayo dentro de la publicación. La evaluación se divide en cinco categorías que se presentan a continuación.
3/4
Randomization
2/4
Outcome Measurements
4/4
Inclusion / Exclusion
4/4
Therapy Description
4/4
Statistics
Detsky AS, Naylor CD, O'Rourke K, McGeer AJ, L'Abbé KA. J Clin Epidemiol. 1992;45:255-65
El Índice de Fragilidad es una herramienta que ayuda en la interpretación de hallazgos significativos, proporcionando una medida de fuerza para un resultado. El Índice de Fragilidad representa el número de eventos consecutivos que es necesario añadir a un resultado dicotómico para que el hallazgo deje de ser significativo. Un número pequeño representa un hallazgo más débil y un número grande un hallazgo más fuerte.
¿Por qué se necesitaba ahora este estudio?
Sciatica resulting from a herniated disc causes radiating pain down the leg. In Western countries, the incidence of sciatica per year is about 5/1000 adults, and this disorder has a large effect on the economy. With regards to cost of hospital care, disorders of the lumbar spine are in the top 5 of disease categories, and also cause increased lost work time and disability. It is widely accepted that surgery should only be performed if conservative treatment has not been successful in reducing symptoms. However, the optimal length of conservative treatment required before surgery is unknown.
¿Cuál era la pregunta principal de la investigación?
In patients presenting with severe sciatica, is earlier surgery more effective in improving outcomes than prolonged conservative treatment, measured over a one year period?
- Over the 52 week follow up period, there were no significant differences between both groups with respect to the Roland Disability Questionnaire (p=0.13).
- Those who underwent early surgery had a significant decrease in leg pain compared to the prolonged conservative treatment group (p<0.001).
- During the first 36 weeks, a faster rate of perceived recovery was observed in the early surgery group (hazard ratio 1.97, 95% CI 1.72 to 2.22, p<0.001).
- After 52 weeks, both groups had similar recovery rates of 95%.
¿Qué es lo que más debo recordar?
At the one year period, both the group undergoing early surgery, and those receiving conservative treatment reported similar outcomes. However, perceived recovery and pain relief were faster for those patients who underwent early surgery.
¿Cómo afectará esto al cuidado de mis pacientes?
Although both patients treated with early surgery and those who received conservative treatment (and eventual surgery if required) produced similar outcomes at one year, early surgery may be a viable option if patients cannot cope with the leg pain, want to reduce recovery time or do not wish to wait for natural recovery to occur. On the other hand, individuals whose pain is tolerable have the option to defer surgery until absolutely necessary. Further high-quality evidence is required to substantiate these findings.
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