Noninferiority of Posterior Cervical Foraminotomy vs Anterior Cervical Discectomy With Fusion for Procedural Success and Reduction in Arm Pain Among Patients With Cervical Radiculopathy at 1 Year: The FACET Randomized Clinical Trial.

この研究はインパクトが大きい可能性があると判断されました。 OEのAIによるハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文の影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することができ、読者は将来の診療を形成する可能性が最も高い論文に焦点を当てることができます。

研究概要

Two hundred and sixty-five patients with cervical radiculopathy were included in this randomized trial assessing the non-inferiority of posterior cervical foraminotomy (n=132) compared to anterior cervical discectomy with fusion (n=133). The primary outcomes of interest were success rate (excellent or good on the Odom criteria) and arm pain on a Visual Analog Scale (VAS), tested for non-inferiority (with corresponding 1-sided confidence intervals [CIs]). Secondary outcomes and safety-outcomes were tested for superiority (with corresponding 2-sided CIs). Outcomes were assessed at 1 year post-operation. Posterior surgery was found to be non-inferior with respect to both arm pain and success rate compared to anterior surgery. However, the change from baseline in arm pain scores was not found to be non-inferior; the difference between groups was not clinically relevant, based on the proportion of patients who reached the minimal clinically important difference. No differences in secondary or safety outcomes were observed. Thus, posterior cervical foraminotomy can be considered as a non-inferior clinical alternative to anterior cervical discectomy with fusion based on the results of this study.