Imrecoxib versus celecoxib as postoperative analgesia for patients receiving arthroscopic knee surgery: a randomized, controlled, non-inferiority study

研究概要

One hundred and twenty-six patients undergoing arthroscopic knee surgery were randomized in this non-inferiority trial to receive either imrecoxib (n=64) or celecoxib (n=62). The primary outcome of interest pain scores on a Visual Analog Scale (VAS), measured at rest and during movement up to 72 hours post-operation. Secondary outcomes of interest included pethidine administration, patient satisfaction, Lysholm scores, and the rate of adverse events. No significant differences were observed between the two groups in all outcomes: imrecoxib was found to be non-inferior to celecoxib for post-operative analgesia.