Effect of Telephone Cognitive Behavioral Therapy for Insomnia in Older Adults With Osteoarthritis Pain: A Randomized Clinical Trial

この研究はインパクトが大きい可能性があると判断されました。 OEのAIによるハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文の影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することができ、読者は将来の診療を形成する可能性が最も高い論文に焦点を当てることができます。

研究概要

Three hundred and twenty-seven patients ≥60 years old and diagnosed with osteoarthritis (OA) and insomnia were randomized to undergo 8 weeks of telephone-delivered cognitive behavioural therapy for insomnia (CBT-I; n=163) or education only (n=164). The primary outcome of interest was severity of insomnia measured on the Insomnia Severity Index (ISI) at 2 months and 12 months follow-up. Secondary outcomes of interest included arthritis pain and interference with activities using the Brief Pain Inventory short form (BPI-sf), depression using the Patient Health Questionnaire (PHQ-8), and fatigue was measured on the Flinders Fatigue Scale (FFS). Moreover, incidence of adverse and serious adverse events were recorded. The rate of adherence of interventions was 80% and 89.6% in the CBT-I and control groups, respectively. Insomnia severity index scores and fatigue severity scores were significantly reduced in the CBT-I group vs control at both timepoints (p<0.05 for all). Depression scores on the PHQ, BPI-sf activity interference, and BPI-sf pain severity scores were significantly in favour of the CBT-I group vs control at 2 months (p<0.05 for all) but not at 12 months follow-up (p>0.05 for both). In both groups, 27 serious adverse events were observed from baseline to 12 months follow-up, none of which were treatment-related.