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Musculoskeletal Evidence
Arthroplasty
Efficacy of Tranexamic Acid in Reducing Blood Loss and Transfusion Requirements in Primary Total Knee Arthroplasty: A Prospective Comparative Study.
J Orthop Case Rep. 2026 01-Jun;():. 10.13107/jocr.2026.v16.i06.7382
Efficacy of Tranexamic Acid in Reducing Blood Loss and Transfusion Requirements in Primary Total Knee Arthroplasty: A Prospective Comparative Study.
J Orthop Case Rep. 2026 01-Jun;():. 10.13107/jocr.2026.v16.i06.7382
Trauma
A Liberal Transfusion Threshold Leads to Higher Infection Rates, Orthopaedic Trauma and Anemia: Conservative Versus Liberal Transfusion Strategy (ORACL), A Prospective Randomized Study 30-Day Inpatient Complications
A Liberal Transfusion Threshold Leads to Higher Infection Rates, Orthopaedic Trauma and Anemia: Conservative Versus Liberal Transfusion Strategy (ORACL), A Prospective Randomized Study 30-Day Inpatient Complications
Peri-Operative
The Effect of Preoperative Intravenous Iron Supplementation on Mortality and Blood Transfusion Requirements in Elderly Patients Undergoing Hip Fracture Surgery: A Prospective Randomized Controlled Trial.
J Clin Med. 2025 01-Jul;():. 10.3390/jcm14134713
The Effect of Preoperative Intravenous Iron Supplementation on Mortality and Blood Transfusion Requirements in Elderly Patients Undergoing Hip Fracture Surgery: A Prospective Randomized Controlled Trial.
J Clin Med. 2025 01-Jul;():. 10.3390/jcm14134713
Arthroplasty
The Effect of Intravenous Tranexamic Acid on Perioperative Blood Loss, Transfusion Requirements, Verticalization, and Ambulation in Total Knee Arthroplasty: A Randomized Double-Blind Study.
Medicina (Kaunas). 2024 01-Jul;():. 10.3390/medicina60071183
The Effect of Intravenous Tranexamic Acid on Perioperative Blood Loss, Transfusion Requirements, Verticalization, and Ambulation in Total Knee Arthroplasty: A Randomized Double-Blind Study.
Medicina (Kaunas). 2024 01-Jul;():. 10.3390/medicina60071183
Trauma
Early Results of Orthopaedic Trauma and Anemia: Conservative Versus Liberal Transfusion Strategy.
J Am Acad Orthop Surg. 2024 01-Mar;():. 10.5435/JAAOS-D-23-00235
Early Results of Orthopaedic Trauma and Anemia: Conservative Versus Liberal Transfusion Strategy.
J Am Acad Orthop Surg. 2024 01-Mar;():. 10.5435/JAAOS-D-23-00235
Trauma
Tranexamic Acid Administered at Time of Hospital Admission Does Not Decrease Transfusion Rates or Blood Loss for Extracapsular Hip Fractures: A Double-Blinded Randomized Clinical Trial
Tranexamic Acid Administered at Time of Hospital Admission Does Not Decrease Transfusion Rates or Blood Loss for Extracapsular Hip Fractures: A Double-Blinded Randomized Clinical Trial
Trauma
Liberal Transfusion Causes Higher Infection Rates With No Benefit to Functional Outcomes, Orthopaedic Trauma, and Anemia: Conservative Versus Liberal Transfusion (ORACL): A Prospective Randomized Study
Liberal Transfusion Causes Higher Infection Rates With No Benefit to Functional Outcomes, Orthopaedic Trauma, and Anemia: Conservative Versus Liberal Transfusion (ORACL): A Prospective Randomized Study
Trauma
OTA 2023: TXA for Blood Loss and Transfusion Rates for Femur Fractures
OTA 2023: TXA for Blood Loss and Transfusion Rates for Femur Fractures
Arthroplasty
Does the accelerometer-based navigation system reduce blood loss and transfusion in one-stage sequential bilateral total knee arthroplasty? A randomized double-blind controlled trial.
BMC Musculoskelet Disord. 2023 01-Jun;():. 10.1186/s12891-023-06648-8
Does the accelerometer-based navigation system reduce blood loss and transfusion in one-stage sequential bilateral total knee arthroplasty? A randomized double-blind controlled trial.
BMC Musculoskelet Disord. 2023 01-Jun;():. 10.1186/s12891-023-06648-8
Trauma
Liberal Transfusion Threshold Leads to Higher Infection Rates, Orthopaedic Trauma, and Anemia: Conservative vs. Liberal Transfusion Strategy (ORACL), a Prospective Randomized Study 30-Day Inpatient Complications
Liberal Transfusion Threshold Leads to Higher Infection Rates, Orthopaedic Trauma, and Anemia: Conservative vs. Liberal Transfusion Strategy (ORACL), a Prospective Randomized Study 30-Day Inpatient Complications
General Orthopaedics
Liberal blood transfusion strategies and associated infection in orthopedic patients: A meta-analysis
Medicine (Baltimore) . 2021 12-Mar;():. 10.1097/MD.0000000000024430
Liberal blood transfusion strategies and associated infection in orthopedic patients: A meta-analysis
Medicine (Baltimore) . 2021 12-Mar;():. 10.1097/MD.0000000000024430
Peri-Operative
Single dose of tranexamic acid effectively reduces blood loss and transfusion rates in elderly patients undergoing surgery for hip fracture: a randomized controlled trial
Bone Joint J. 2021 01-Mar;():. 10.1302/0301-620X.103B3.BJJ-2020-1288.R1
Single dose of tranexamic acid effectively reduces blood loss and transfusion rates in elderly patients undergoing surgery for hip fracture: a randomized controlled trial
This report has been verified by one or more authors of the original publication.
Bone Joint J. 2021 01-Mar;():. 10.1302/0301-620X.103B3.BJJ-2020-1288.R1
General Orthopaedics
Intravenous tranexamic acid reduces blood loss and transfusion requirements after periacetabular osteotomy
Bone Joint J. 2020 01-Sep;():. 10.1302/0301-620X.102B9.BJJ-2019-1777.R1
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
Intravenous tranexamic acid reduces blood loss and transfusion requirements after periacetabular osteotomy
This report has been verified by one or more authors of the original publication.
Bone Joint J. 2020 01-Sep;():. 10.1302/0301-620X.102B9.BJJ-2019-1777.R1
Spine
Effectiveness of bone marrow-derived mononuclear stem cells for neurological recovery in participants with spinal cord injury: A randomized controlled trial
Asian J Transfus Sci. 2019 ;():. 10.4103/ajts.AJTS_44_18.
Effectiveness of bone marrow-derived mononuclear stem cells for neurological recovery in participants with spinal cord injury: A randomized controlled trial
Asian J Transfus Sci. 2019 ;():. 10.4103/ajts.AJTS_44_18.
Physical Therapy & Rehab
Efficacy of platelet-rich plasma as conservative treatment in orthopaedics: a systematic review and meta-analysis
Blood Transfus. 2018 Nov;16(6):502-513.
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
Efficacy of platelet-rich plasma as conservative treatment in orthopaedics: a systematic review and meta-analysis
Blood Transfus. 2018 Nov;16(6):502-513.
General Orthopaedics
Safety of intravenous tranexamic acid in patients undergoing major orthopaedic surgery: a meta-analysis of randomised controlled trials
Blood Transfus. 2018 Jan;16(1):36-43
Safety of intravenous tranexamic acid in patients undergoing major orthopaedic surgery: a meta-analysis of randomised controlled trials
Blood Transfus. 2018 Jan;16(1):36-43
Arthroplasty
No Difference in Blood Loss, Transfusion in Navigated and Non-Navigated Bilateral Knee Arthroplasty: A Prospective Randomized Study
No Difference in Blood Loss, Transfusion in Navigated and Non-Navigated Bilateral Knee Arthroplasty: A Prospective Randomized Study
Arthroplasty
Topical use of topical fibrin sealant can reduce the need for transfusion, total blood loss and the volume of drainage in total knee and hip arthroplasty: A systematic review and meta-analysis of 1489 patients
Int J Surg. 2016 Dec;36(Pt A):127-137
Topical use of topical fibrin sealant can reduce the need for transfusion, total blood loss and the volume of drainage in total knee and hip arthroplasty: A systematic review and meta-analysis of 1489 patients
Int J Surg. 2016 Dec;36(Pt A):127-137
Arthroplasty
The efficacy and safety of autologous blood transfusion drainage in patients undergoing total knee arthroplasty: a meta-analysis of 16 randomized controlled trials
BMC Musculoskelet Disord. 2016 Nov 2;17(1):452
The efficacy and safety of autologous blood transfusion drainage in patients undergoing total knee arthroplasty: a meta-analysis of 16 randomized controlled trials
This report has been verified by one or more authors of the original publication.
BMC Musculoskelet Disord. 2016 Nov 2;17(1):452
Arthroplasty
Erythropoietin to reduce allogeneic red blood cell transfusion in patients undergoing total hip or knee arthroplasty.
Vox Sang. 2016 Oct;111(3):219-225
Erythropoietin to reduce allogeneic red blood cell transfusion in patients undergoing total hip or knee arthroplasty.
Vox Sang. 2016 Oct;111(3):219-225
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