OrthoEvidence - Search

Arthroplasty
Efficacy of Tranexamic Acid in Reducing Blood Loss and Transfusion Requirements in Primary Total Knee Arthroplasty: A Prospective Comparative Study.
J Orthop Case Rep. 2026 01-Jun;():. 10.13107/jocr.2026.v16.i06.7382

Shoulder & Elbow
Tranexamic acid in arthroscopic repair of rotator cuff tears in the shoulder: a randomized trial.
Rev Assoc Med Bras (1992). 2026 01-Jun;():. 10.1590/1806-9282.20251543

Physical Therapy & Rehab
The Efficacy of Tranexamic Acid in Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-Analysis.
Adv Orthop. 2026 01-Apr;():. 10.1155/aort/9180643

Arthroplasty
Anti-inflammatory effect of multi-dose tranexamic acid in hip and knee arthroplasty: a systematic review and meta-analysis of randomized controlled trials.
Inflammopharmacology. 2025 01-Mar;():. 10.1007/s10787-025-01679-0

Shoulder & Elbow

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Tranexamic acid use in arthroscopic rotator cuff repair is an effective and safe adjunct to improve visualization: a systematic review and meta-analysis.
J Shoulder Elbow Surg. 2023 01-Nov;():. 10.1016/j.jse.2023.06.013

Peri-Operative
Equivalence of oral and intravenous tranexamic acid in knee arthroplasty: a systematic review and meta-analysis of randomized clinical trials.
Int J Surg. 2026 01-Jan;():. 10.1097/JS9.0000000000003347

General Orthopaedics
What is the Best Method of Tranexamic Acid Administration in Extracapsular Hip Fractures? A Meta-analysis of Randomized Controlled Trials

Arthroplasty
No Effects of Extended Oral Tranexamic Acid following Total Knee Arthroplasty on Postoperative Pain and Range of Motion: A Randomized Controlled Trial

Peri-Operative

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Efficacy and Safety of Tranexamic Acid Combined with Absorbable Hemostat in Reducing Perioperative Blood Loss in Total Knee Arthroplasty: A Prospective, Blinded, Randomized Controlled Trial.
J Bone Joint Surg Am. 2025 01-Oct;():. 10.2106/JBJS.24.01236

Shoulder & Elbow
A therapeutic assessment of tranexamic acid on functional recovery after rotator cuff repair surgery: A study of early and mid-term follow-up.
J Orthop. 2025 01-Sep;():. 10.1016/j.jor.2025.02.006

Arthroplasty

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Intravenous Tranexamic Acid Does Not Improve Visual Field Clarity During Hip Arthroscopy: A Double-Blind, Randomized, Placebo-Controlled Trial.
Arthroscopy. 2025 01-Aug;():. 10.1016/j.arthro.2025.01.008

Shoulder & Elbow
Preoperative Intravenous Carbazochrome Sodium Sulfonate Improves Visual Clarity in Patients Undergoing Arthroscopic Rotator Cuff Repair Compared to Tranexamic Acid and Sodium Chloride: A Randomized Controlled, Triple-Blinded, Prospective Study.
Arthroscopy. 2025 01-Aug;():. 10.1016/j.arthro.2025.01.051

Trauma
Intramedullary administration of tranexamic acid reduces bleeding in proximal femoral nail antirotation surgery for intertrochanteric fractures in elderly individuals: A randomized controlled trial.
Chin J Traumatol. 2025 01-May;():. 10.1016/j.cjtee.2024.01.006

Trauma
Efficacy of intraoperative use of tranexamic acid in reducing blood loss from telescoping nail application in osteogenesis imperfecta. A randomized controlled trial.
Orthop Traumatol Surg Res. 2025 01-May;():. 10.1016/j.otsr.2024.103927

Arthroplasty
The effect of tranexamic acid on blood coagulation in primary total hip arthroplasty using rotational thromboelastometry: a randomized controlled trial.
EClinicalMedicine. 2025 01-Jul;():. 10.1016/j.eclinm.2025.103374

Osteoarthritis
The role of tranexamic acid and cryotherapy on acute postoperative pain and blood loss: a randomized controlled study following total knee arthroplasty.
Eur J Orthop Surg Traumatol. 2025 01-Jan;():. 10.1007/s00590-025-04174-y

Shoulder & Elbow
Tranexamic Acid and Heterotopic Ossification Formation Following Elbow Surgery: A Prospective Randomized Controlled Trial.
J Orthop Trauma. 2025 01-May;():. 10.1097/BOT.0000000000002963

Peri-Operative
Efficacy of preoperative Tranexamic Acid in patients undergoing intertrochanteric hip fracture surgery: A randomized placebo controlled trial.
Pak J Med Sci. 2023 01-Nov;():. 10.12669/pjms.39.6.7667

Trauma
Efficacy and Safety of Topical Tranexamic Acid in Elderly Hip Fractures Undergoing Surgical Treatment: Meta-Analysis of Randomized Controlled Trials.
Clin Orthop Surg. 2025 01-Feb;():. 10.4055/cios24184

Spine
Comparing the efficacy and safety of oral versus intravenous tranexamic acid in spine surgery: a systematic review and meta-analysis of randomized controlled trials.
Neurosurg Rev. 2025 01-May;():. 10.1007/s10143-025-03637-4