Tranexamic acid reduces blood transfusion requirements during surgery

BMJ. 2012 May 17;344:e3054. doi: 10.1136/bmj.e3054

Tranexamic Acid Reduces Blood Loss and Blood Transfusion after TKA

Clin Orthop Relat Res. 2011 Oct;469(10):2874-80. Epub 2011 Apr 22

Tranexamic acid is effective in reducing blood loss, while maintaining safety, in THA

Arch Orthop Trauma Surg. 2013 Jul;133(7):1017-27. doi: 10.1007/s00402-013-1761-2. Epub 2013 Apr 25

Efficacy of Floseal vs. tranexamic acid vs. control for bleeding control in patients undergoing TKA

Clinics (Sao Paulo). 2019 Nov 25;74:e1186.

AAOS 2016: Interim evaluation of tranexamic acid vs placebo in acetabular fracture surgery

AAOS2017: Tranexamic acid appears safe and effective in fracture surgery

TKA: Topical Fibrin Spray and Tranexamic acid reduce blood loss

J Bone Joint Surg Br. 2007 Mar;89(3):306-9

Efficacy of various tranexamic acid administration techniques to reduce blood loss in TKA

Knee Surg Sports Traumatol Arthrosc. 2014 Dec;22(12):3181-90.

Tranexamic acid is safe and effective in reducing blood loss in TKA

J Bone Joint Surg Am. 2012 Jul 3;94(13):1153-9. doi: 10.2106/JBJS.K.00873

COA2017: IA TXA and IV TXA demonstrate similar results for blood loss in total hip arthroplasty

Tranexamic acid effectively reduces blood loss after TKA without adverse events

Knee Surg Sports Traumatol Arthrosc. 2014 Aug;22(8):1849-58

TKR: Topical application of tranexamic acid reduces postoperative blood loss

J Bone Joint Surg Am. 2010 Nov 3;92(15):2503-13.

TKA: Intra-articular tranexamic acid reduces blood loss and transfusion requirements

Knee Surg Sports Traumatol Arthrosc. 2012 Dec;20(12):2494-501. doi: 10.1007/s00167-012-1942-5. Epub 2012 Mar 15

AAOS 2015: Tranexamic acid effectively lowers blood loss following TKA without tourniquet

3 doses of tranexamic acid more effective regimen in TKA

Clin Orthop Relat Res. 2012 Sep;470(9):2605-12. doi: 10.1007/s11999-012-2310-y. Epub 2012 Mar 15.

IV tranexamic acid reduces blood loss and transfusion rate in primary THA

Orthopedics. 2016 Sep 1;39(5):e883-92

AAOS2018: TXA effective in operative management for high-energy pelvic and femoral fractures

AAOS 2015: No difference between topical and intravenous tranexamic acid for TKA

Intravenous TXA prior to tourniquet inflation more efficacious compared to later timepoints

J Arthroplasty. 2017 Jan;32(1):33-36

AAOS 2016: TXA vs. epsilon-aminocaproic acid provide comparable outcomes after TKA