Tranexamic acid reduces blood transfusion requirements during surgery

BMJ. 2012 May 17;344:e3054. doi: 10.1136/bmj.e3054

Tranexamic Acid Reduces Blood Loss and Blood Transfusion after TKA

Clin Orthop Relat Res. 2011 Oct;469(10):2874-80. Epub 2011 Apr 22

Tranexamic acid is effective in reducing blood loss, while maintaining safety, in THA

Arch Orthop Trauma Surg. 2013 Jul;133(7):1017-27. doi: 10.1007/s00402-013-1761-2. Epub 2013 Apr 25

AAOS2017: Tranexamic acid appears safe and effective in fracture surgery

3 doses of tranexamic acid more effective regimen in TKA

Clin Orthop Relat Res. 2012 Sep;470(9):2605-12. doi: 10.1007/s11999-012-2310-y. Epub 2012 Mar 15.

AAOS 2016: Interim evaluation of tranexamic acid vs placebo in acetabular fracture surgery

TKA: Topical Fibrin Spray and Tranexamic acid reduce blood loss

J Bone Joint Surg Br. 2007 Mar;89(3):306-9

Tranexamic acid is safe and effective in reducing blood loss in TKA

J Bone Joint Surg Am. 2012 Jul 3;94(13):1153-9. doi: 10.2106/JBJS.K.00873

AAOS 2016: TXA vs. epsilon-aminocaproic acid provide comparable outcomes after TKA

AAOS: Tranexamic acid equally effective when administered topically & intravenously in TKA

Lower blood loss with IV+IA TXA versus IV TXA alone following total knee arthroplasty

J Bone Joint Surg Am. 2016 May 18;98(10):835-41

Tranexamic acid reduces blood loss and transfusions in TKA and THA

BMC Res Notes. 2013 May 7;6:184. doi: 10.1186/1756-0500-6-184

Tranexamic acid effectively reduces blood loss after TKA without adverse events

Knee Surg Sports Traumatol Arthrosc. 2014 Aug;22(8):1849-58

TKR: Topical application of tranexamic acid reduces postoperative blood loss

J Bone Joint Surg Am. 2010 Nov 3;92(15):2503-13.

COA2017: IA TXA and IV TXA demonstrate similar results for blood loss in total hip arthroplasty

Efficacy of various tranexamic acid administration techniques to reduce blood loss in TKA

Knee Surg Sports Traumatol Arthrosc. 2014 Dec;22(12):3181-90.

AAOS 2015: Tranexamic acid effectively lowers blood loss following TKA without tourniquet

IV tranexamic acid reduces blood loss and transfusion rate in primary THA

Orthopedics. 2016 Sep 1;39(5):e883-92

AAOS 2015: No difference between topical and intravenous tranexamic acid for TKA

OTA2018: Tranexamic acid effective for reducing blood loss in nailing of intertrochanteric fracture