OrthoEvidence - Search

Arthroplasty
Does Liposomal Bupivacaine Provide Superior Postoperative Analgesia Compared With Ropivacaine With Dexamethasone in Suprainguinal Fascia Iliaca Compartment Block for THA? A Randomized Controlled Trial.
Clin Orthop Relat Res. 2026 07-Sep;():. 10.1097/CORR.0000000000003907

Arthroplasty
Dexamethasone vs. Dexmedetomidine as Adjuvants to Erector Spinae Plane Block in Total Knee Arthroplasty: A Randomized Double-Blind Controlled Trial.
J Clin Med. 2026 01-Jun;():. 10.3390/jcm15124513

Arthroplasty
Intravenous Dexamethasone Administered Perioperatively vs 8 Hours Prior to Incision to Control Pain after Total Knee Arthroplasty. A Prospective Randomized Clinical Trial.
Arthroplast Today. 2025 01-Dec;():. 10.1016/j.artd.2025.101912

Arthroplasty
Reduced Ropivacaine Volume with Perineural Dexamethasone in PENG Block for Total Hip Arthroplasty: A Randomized Controlled Trial.
J Clin Med. 2025 01-Dec;():. 10.3390/jcm14248722

Arthroplasty

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Oral Corticosteroids Reduce Pain After Total Knee Arthroplasty: A Higher Dose of Dexamethasone Effectively Controlled Pain During Motion: A Dose-Response Randomized Placebo-Controlled Trial.
J Bone Joint Surg Am. 2026 01-Jan;():. 10.2106/JBJS.25.00642

Foot & Ankle
Comparing Single-Shot Liposomal Bupivacaine vs. Liposomal Bupivacaine Combined with Dexamethasone for Foot and Ankle Procedures

Arthroplasty
Perineural dexamethasone enhances analgesic duration of erector spinae plane block in total hip arthroplasty: A randomized quadruple-blind controlled trial.
J Orthop. 2025 01-Aug;():. 10.1016/j.jor.2025.08.033

Arthroplasty

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

The James A. Rand Young Investigator's Award: What Is the Safest and Most Effective Dose of Intravenous Dexamethasone in Total Knee Arthroplasty? A Multicenter Randomized Controlled Trial.
J Arthroplasty. 2025 01-Sep;():. 10.1016/j.arth.2025.04.068

Arthroplasty
Perineural dexamethasone effectively prolongs anaesthesic block duration in total hip arthroplasty, reduces opioid consumption, and does not compromise motor function, nerve integrity, or glycaemic control.
Int Orthop. 2025 01-Aug;():. 10.1007/s00264-025-06578-1

Arthroplasty
Comparison of analgesic effects between betamethasone and dexamethasone in total knee arthroplasty: a prospective randomized controlled trial.
Front Med (Lausanne). 2025 01-Jul;():. 10.3389/fmed.2025.1575417

Arthroplasty
A Single Preoperative Low Dose of Dexamethasone Is Efficacious in Improving Early Postoperative Pain, Function, Nausea, and Vomiting After Primary Total Knee Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial.
J Arthroplasty. 2025 01-Jul;():. 10.1016/j.arth.2024.11.061

Hand & Wrist
The effect of intravenous dexamethasone on rebound pain after wrist and hand surgery under supraclavicular brachial plexus blockade: a randomized placebo-controlled trial.
Can J Anaesth. 2025 01-Jul;():. 10.1007/s12630-025-02992-6

Arthroplasty
Repeat-dose dexamethasone to prevent pain relapse after total knee arthroplasty in high-pain-response patients: A randomised, double-blind, placebo-controlled superiority trial.
Eur J Anaesthesiol. 2025 01-Jul;():. 10.1097/EJA.0000000000002189

Spine
Effects of dexamethasone combined with vitamin B12 on percutaneous endoscopic interlaminar discectomy early outcomes: a randomized controlled trial.
J Orthop Surg Res. 2024 01-Nov;():. 10.1186/s13018-024-05210-z

Spine
Dexamethasone Plus Bupivacaine Versus Bupivacaine in Bilateral Transincisional Paravertebral Block in Lumbar Spine Surgeries: A Randomized Controlled Trial.
Clin J Pain. 2023 01-Sep;():. 10.1097/AJP.0000000000001141

Hand & Wrist

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Exploring the Additive or Synergistic Effects of the Systemic and Perineural Routes of Dexamethasone as Adjuncts to Supraclavicular Block: A Randomized Controlled Trial.
Anesthesiology. 2025 01-Jun;():. 10.1097/ALN.0000000000005433

Peri-Operative
Effect of high-dose dexamethasone on morphine use after periacetabular osteotomy for hip dysplasia: a randomized double-blind placebo-controlled single center trial.
Acta Orthop. 2025 01-Jun;():. 10.2340/17453674.2025.43903

Shoulder & Elbow
Comparison between bupivacaine-lidocaine, dexamethasone mixture and bupivacaine alone for motor recovery after axillary brachial plexus block in distal radius surgery: A prospective randomized trial.
PLoS One. 2025 01-Apr;():. 10.1371/journal.pone.0321087

Peri-Operative
Perioperative Dexamethasone Split Between Two Doses Further Reduced Early Postoperative Nausea and Vomiting Than Single-Dose Dexamethasone: A Randomized Blinded Placebo-Controlled Trial.
J Arthroplasty. 2024 01-Dec;():. 10.1016/j.arth.2024.07.029

Arthroplasty

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Intravenous Dexamethasone Transiently Elevates Blood Glucose Levels and Reduces Pain After TKA in Patients with Type-2 Diabetes Mellitus: A Randomized Controlled Study.
J Bone Joint Surg Am. 2025 01-May;():. 10.2106/JBJS.24.00984