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Vitamin D: Why is the ‘Sunshine Vitamin’ Getting So Much Shade?
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RESEARCH

Vitamin D: Why is the ‘Sunshine Vitamin’ Getting So Much Shade ?

Vitamin D is critical for calcium metabolism, immune regulation, and musculoskeletal health, yet clinical evidence supporting its broader use remains inconclusive. While observational studies link low vitamin D levels to various conditions, randomized trials often show little to no benefit—especially for musculoskeletal outcomes like pain, function, or fracture prevention. There remains a disconnect between correlation and causation, observed by highlighting ongoing orthopaedic trials and presenting meta-analytic findings showing no significant benefit of vitamin D in osteoarthritis patients. Though supplementation remains important to prevent deficiency, routine use for orthopaedic outcomes lacks strong support.

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  • Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
  • Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
  • Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
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OrthoEvidence. Vitamin D: Why is the ‘Sunshine Vitamin’ Getting So Much Shade?. OE Original. 2024. Available from: https://dev-specialtypages-demo.azurewebsites.net/Original/Show/vitamin-d-why-is-the-sunshine-vitamin-getting-so-much-shade

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