RESEARCH
Prolotherapy for Rotator Cuff Tendinopathy: Powered by OE M.I.N.D. .
Prolotherapy, an injection-based regenerative therapy using dextrose or glucose, was evaluated for treating rotator cuff tendinopathy through meta-analysis of 9 RCTs. Compared to control (placebo or physical therapy), prolotherapy led to small but statistically significant improvements in pain and composite outcomes at short- and long-term follow-up, though these did not exceed established thresholds for clinical importance. Corticosteroid injections outperformed prolotherapy in composite outcomes within 6 months, but not beyond. Pain relief was similar between groups at all time points. No serious adverse events were reported, and evidence certainty ranged from low to moderate.
Already have an account? Log in
Unlock the Full original article
You have access to 4 more FREE articles this month.
Click below to unlock and view this original article
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
