Platelet Rich Plasma and Stem Cell Therapy: Setting Standards and Evidence .

Biologics such as platelet-rich plasma (PRP) and stem cell therapies are increasingly used in orthopaedic care, yet high-quality evidence supporting their efficacy remains limited. This piece examines current scientific and regulatory challenges, including inconsistencies in PRP preparation, lack of standardized protocols, and methodological issues in clinical trials. Emphasis is placed on the need for rigorous evaluation and evidence-based guidance to support safe and effective integration into clinical practice.