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Evidence Based Medicine
Clinical Trials That Moved the Needle: Top Evidence Trends from 2023
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Clinical Trials That Moved the Needle: Top Evidence Trends from 2023 .

Ellen Scholl

et al.

Click here to list additional authors

/ Dec 28, 2023
This OE Insight highlights five landmark RCTs from 2023 that shifted orthopaedic practice. The OPAL trial found opioids ineffective for acute back/neck pain. BUCKLED showed ultrasound is non-inferior to X-rays for pediatric forearm fractures. INSITE challenged the superiority of intramedullary nails. WHiTE 8 found no benefit of dual-antibiotic cement. PREVENT CLOT supported aspirin as a cost-effective alternative to LMWH for thromboprophylaxis. Each trial pushes the field toward safer, more efficient care.

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Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics

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  • Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
  • Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
  • Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
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OrthoEvidence. Clinical Trials That Moved the Needle: Top Evidence Trends from 2023. OE Original. 2023. Available from: https://myorthoevidence.com/Original/Show/clinical-trials-that-moved-the-needle-top-evidence-trends-from-2023

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