Postmenopausal women may represent a distinct risk group for meniscus posterior root tears (MPRTs), according to emerging clinical evidence. The report highlights how hormonal changes and declining bone quality following menopause may contribute to degenerative meniscal root injuries, particularly in the medial meniscus. These tears can disrupt normal knee biomechanics, leading to increased joint loading and accelerated cartilage degeneration that may progress toward osteoarthritis. Findings suggest that clinicians should consider sex-specific risk factors and degenerative mechanisms when evaluating knee pain in older women. Earlier recognition and targeted interventions—ranging from structured rehabilitation to surgical repair in selected cases—may help preserve joint function and potentially slow disease progression in this vulnerable population.