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Ozempic in Orthopedics: Weight Loss Miracle or a Musculoskeletal Risk?

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March 19, 2025

Ozempic in Orthopedics: Weight Loss Miracle or a Musculoskeletal Risk?

Vol: 10| Issue: 2| Number:1| ISSN#: 2563-559X
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From Oprah Winfrey to Charles Barkley to Billie Jean King – if you don’t know someone who’s tried it, you know someone who knows someone who’s tried it.  Of course, we are talking about GLP-1 receptor agonists (GLP-1 RAs), but you probably know it by the most popular brand name formulation: Ozempic. GLP 1 agonists like Ozempic have taken the world by a storm in recent years, with many touting it as a revolution in health care and weight loss management. Originally developed as a diabetes drug, the demand for GLP-1s for weight-loss purposes is so strong that black markets have been created to fill the gap[1]. However, as their use expands, evidence on their potential effects on the musculoskeletal system has been coming to light; recent studies have reported that GLP1-RAs could be decreasing.....
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