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Rofecoxib and celecoxib demonstrate similar, significant 6-week efficacy vs placebo in OA treatment
September 2017
Rofecoxib and celecoxib demonstrate similar, significant 6-week efficacy vs placebo in OA treatment
Study Type:Therapy
OE Level Evidence:N/A
Journal Level of Evidence:N/A
Efficacy and safety of rofecoxib 12.5 mg and celecoxib 200 mg in two similarly designed osteoarthritis studies
Curr Med Res Opin. 2006 Jan;22(1):199-210Synopsis
808 patients, combined from two trials, with knee osteoarthritis were randomized to receive either celecoxib 200mg daily, rofecoxib 12.5mg daily, or placebo. Patients were assessed over a 6-week period of treatment on a Patient Global Assessment of Response to Therapy (PGART), the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain and Physical Function subscales, and the i...
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