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Efficacy of pregabalin for immediate postoperative pain and opioid consumption after THA
May 2016
Efficacy of pregabalin for immediate postoperative pain and opioid consumption after THA
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Pregabalin reduces postoperative opioid consumption and pain for 1 week after hospital discharge, but does not affect function at 6 weeks or 3 months after total hip arthroplasty
Br J Anaesth. 2015 Dec;115(6):903-11Synopsis
184 patients scheduled for total hip arthroplasty were randomized to receive a predetermined perioperative analgesic regimen (spinal anesthesia and celecoxib) with or without the addition of pregabalin. The purpose of this study was to analyze the benefits of pregabalin when compared to a placebo in terms of pain, function and postoperative opioid consumption. The results of this study demonstrate...
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