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Efficacy of pregabalin for immediate postoperative pain and opioid consumption after THA

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Ace Report Cover
May 2016

Efficacy of pregabalin for immediate postoperative pain and opioid consumption after THA

Vol: 5| Issue: 5| Number:33| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Pregabalin reduces postoperative opioid consumption and pain for 1 week after hospital discharge, but does not affect function at 6 weeks or 3 months after total hip arthroplasty

Br J Anaesth. 2015 Dec;115(6):903-11

Contributing Authors:
H Clarke GM Pagé CJ McCartney A Huang P Stratford J Andrion D Kennedy IT Awad J Gollish J Kay J Katz

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Synopsis

184 patients scheduled for total hip arthroplasty were randomized to receive a predetermined perioperative analgesic regimen (spinal anesthesia and celecoxib) with or without the addition of pregabalin. The purpose of this study was to analyze the benefits of pregabalin when compared to a placebo in terms of pain, function and postoperative opioid consumption. The results of this study demonstrate...

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