Ifosfamide-based chemotherapy yields high survival rate for treatment of osteosarcoma

Study Type:Meta analysis

OE Level Evidence:1

Journal Level of Evidence:N/A

Efficacy and safety of ifosfamide-based chemotherapy for osteosarcoma: a meta-analysis

Drug Des Devel Ther. 2015 Nov 4;9:5925-32

Contributing Authors: XL Fan GP Cai LL Zhu GM Ding

Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here

Synopsis

Seven randomized controlled trials with 2,529 patients with histologically confirmed osteosarcoma were included in this meta-analysis. The purpose of this study was to compare the safety and efficacy of ifosfamide-based chemotherapy to a control group receiving chemotherapy without ifosfamide. The results displayed that ifosfamide-based chemotherapy had significantly higher event-free survival, ov...