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Topical TXA found safe and effective for reduction of blood loss and transfusion in TKA

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Ace Report Cover
August 2015

Topical TXA found safe and effective for reduction of blood loss and transfusion in TKA

Vol: 4| Issue: 8| Number:19| ISSN#: 2564-2537
Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A

Effect of Topical Tranexamic Acid in Reducing Bleeding and Transfusions in TKA

Orthopedics. 2015 May 1;38(5):315-24.

Contributing Authors:
C Yue F Pei P Yang J Xie P Kang

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Synopsis

12 studies including 1179 knees, evaluated topical tranexamic acid (TXA) administration versus a control in total knee arthroplasty. The goal of this meta-analysis was to determine the safety and efficacy of topical administration of TXA in total knee arthroplasty. The results revealed that topical administration of TXA significantly decreased total blood loss, transfusion rate, postoperative drai...

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