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Combined Topical & IV TXA superior to topical TXA alone for reducing blood loss in TKA
July 2016
Combined Topical & IV TXA superior to topical TXA alone for reducing blood loss in TKA
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
The Efficacy of Combined Use of Intraarticular and Intravenous Tranexamic Acid on Reducing Blood Loss and Transfusion Rate in Total Knee Arthroplasty
J Arthroplasty. 2015 May;30(5):776-80Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred and twenty patients with a diagnosis of primary osteoarthritis (OA) scheduled for unilateral total knee arthroplasty were randomized to receive either a combination of topical and intravenous administration of tranexamic acid, topical administration alone, or a saline control. Initial hemoglobin levels and postoperative drop, total drain amount, total blood loss, and transfusion rate w...
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