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Combination of intravenous and topical TXA improves outcomes following primary TKA
March 2015
Combination of intravenous and topical TXA improves outcomes following primary TKA
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Combination of intravenous and topical application of tranexamic acid in primary total knee arthroplasty: a prospective randomized controlled trial
J Arthroplasty. 2014 Dec;29(12):2342-6.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
184 patients undergoing unilateral total knee arthroplasty (TKA) were randomized to one of two tranexamic acid groups: an intravenous administration group, or a combined topical and intravenous administration group. Patients in the intravenous group were given 3g of tranexamic acid (TXA) intravenously during surgery. Those in the combined group had a solution composed of 1.5g of TXA and 50mL of no...
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