Combination of intravenous and topical TXA improves outcomes following primary TKA
Combination of intravenous and topical application of tranexamic acid in primary total knee arthroplasty: a prospective randomized controlled trialJ Arthroplasty. 2014 Dec;29(12):2342-6.
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184 patients undergoing unilateral total knee arthroplasty (TKA) were randomized to one of two tranexamic acid groups: an intravenous administration group, or a combined topical and intravenous administration group. Patients in the intravenous group were given 3g of tranexamic acid (TXA) intravenously during surgery. Those in the combined group had a solution composed of 1.5g of TXA and 50mL of no...
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