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ACE Report #7455
Ace Report Cover Arthroplasty

Combination of intravenous and topical TXA improves outcomes following primary TKA

Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Combination of intravenous and topical application of tranexamic acid in primary total knee arthroplasty: a prospective randomized controlled trial

J Arthroplasty. 2014 Dec;29(12):2342-6.

Contributing Authors: Z Huang J Ma B Shen F Pei

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184 patients undergoing unilateral total knee arthroplasty (TKA) were randomized to one of two tranexamic acid groups: an intravenous administration group, or a combined topical and intravenous administration group. Patients in the intravenous group were given 3g of tranexamic acid (TXA) intravenously during surgery. Those in the combined group had a solution composed of 1.5g of TXA and 50mL of no...

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