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ACE Report #656
Ace Report Cover Hand & Wrist

Hylan injection: A potential consideration for the first carpometacarpal joint arthritis

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Hylan Versus Corticosteroid Versus Placebo for Treatment of Basal Joint Arthritis: A Prospective, Randomized, Double-Blinded Clinical Trial

J Hand Surg Am. 2008 Jan;33(1):40-8.

Contributing Authors: BE Heyworth JH Lee PD Kim CB Lipton RJ Strauch MP Rosenwasser

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60 patients, >40 yr old, with basal joint osteoarthritis of the thumb were randomized to receive either intra-articular hylan, corticosteroid, or placebo injection. No major clinically significant differences were apparent between the different treatments. The hylan injection had a persistent effect on pain relief up to week 26 and improved grip strength at this time point.

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