Balloon kyphoplasty more effective than non-surgical treatment in cancer patients with VCF

Study Type:Therapy

OE Level Evidence:2

Journal Level of Evidence:N/A

Balloon kyphoplasty versus non-surgical fracture management for treatment of painful vertebral body compression fractures in patients with cancer: a multicentre, randomised controlled trial

Lancet Oncol. 2011 Mar;12(3):225-35. doi: 10.1016/S1470-2045(11)70008-0. Epub 2011 Feb 16

Contributing Authors: J Berenson R Pflugmacher P Jarzem J Zonder K Schechtman JB Tillman L Bastian T Ashraf F Vrionis Cancer Patient Fracture Evaluation (CAFE) Investigators

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Synopsis

134 patients with metastatic bone disease and a vertebral compression fracture (VCF) were randomized to be treated with either balloon kyphoplasty or a standard non-surgical treatment (control group) to compare the effects of these treatments on pain, function and quality of life. Results indicated that the kyphoplasty group had significantly better improvements in function, quality of life, reduc...