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Bupivacaine provides better post-operative pain relief in comparison to placebo

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Ace Report Cover
June 2013

Bupivacaine provides better post-operative pain relief in comparison to placebo

Vol: 2| Issue: 5| Number:16| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Three-in-one nerve block with different concentrations of bupivacaine in total knee arthroplasty: randomized, placebo-controlled, double-blind trial

J Arthroplasty. 2012 May;27(5):673-8.e1. Epub 2011 Sep 23

Contributing Authors:
Z Xie W Hussain TW Cutter JL Apfelbaum ML Drum DW Manning

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Synopsis

105 patients scheduled to undergo unilateral total knee arthroplasty were randomized to receive either a low dose or a high dose of bupivacaine or a placebo. Results from early post-operative follow-up indicated that patients who received placebo were three times as likely to experience pain. However, this difference between the three groups disappeared at 1 day post-operative follow-up. Additiona...

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