Tranexamic Acid Reduces Blood Loss in Pediatric Osteogenesis Imperfecta Femoral Nailing
Tranexamic Acid Reduces Blood Loss in Pediatric Osteogenesis Imperfecta Femoral Nailing
Efficacy of intraoperative use of tranexamic acid in reducing blood loss from telescoping nail application in osteogenesis imperfecta. A randomized controlled trial.
Orthop Traumatol Surg Res. 2025 01-May;().Synopsis
Forty patients with osteogenesis imperfecta (OI) were randomized to receive intraoperative tranexamic acid (intravenous plus topical) (n=20) or no tranexamic acid (n=20). The primary outcome was total blood loss. Secondary outcomes included changes in hemoglobin and hematocrit, transfusion rate, operative time, and short-term TXA-related complications. Outcomes were assessed intraoperatively and t...
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