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Comparison of the Effects of Metformin & Thiazolidinediones on Bone Metabolism: A Meta-Analysis
June 2024
Comparison of the Effects of Metformin & Thiazolidinediones on Bone Metabolism: A Meta-Analysis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Comparison of the Effects of Metformin and Thiazolidinediones on Bone Metabolism: A Systematic Review and Meta-Analysis.
Medicina (Kaunas) . 2023 May 8;59(5):904.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Seven randomized controlled trials, including 1656 patients with diabetes mellitus, were included in this systematic review and meta-analysis comparing metformin versus thiazolidinediones (TZDs). Pooled outcomes of interest included bone mineral density (BMD), C-terminal telopeptide of type I collagen (CTX), procollagen type I N-terminal propeptide (PINP), bone-specific alkaline phosphatase (BAP),...
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