Oral Vs Intravenous Tranexamic Acid For Perioperative Blood Loss After Total Hip Arthroplasty
Oral Vs Intravenous Tranexamic Acid For Perioperative Blood Loss After Total Hip Arthroplasty
Oral as compared to intravenous tranexamic acid to limit peri-operative blood loss associated with primary total hip arthroplasty: A randomised noninferiority trial.
Eur J Anaesthesiol . 2024 Mar 1;41(3):217-225.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Two hundred and twenty-eight patients with primary total hip arthroplasty were randomized to receive either oral tranexamic acid (oral TXA; n=114) or 1 g of intravenous TXA (IV TXA; n=114). The primary outcome of interest was total blood loss (TBL) intra-operatively and up to 48 hours postoperatively. Secondary outcomes included a hemoglobin concentration decrease, D-Dimer levels on days 1 and 3, ...
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