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Oral Vs Intravenous Tranexamic Acid For Perioperative Blood Loss After Total Hip Arthroplasty

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Ace Report Cover
June 2024

Oral Vs Intravenous Tranexamic Acid For Perioperative Blood Loss After Total Hip Arthroplasty

Vol: 306| Issue: 6| Number:63| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Oral as compared to intravenous tranexamic acid to limit peri-operative blood loss associated with primary total hip arthroplasty: A randomised noninferiority trial.

Eur J Anaesthesiol . 2024 Mar 1;41(3):217-225.

Contributing Authors:
N Piette F Beck M Carella G Hans D Maesen W Kurth JP Lecoq VL Bonhomme

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Synopsis

Two hundred and twenty-eight patients with primary total hip arthroplasty were randomized to receive either oral tranexamic acid (oral TXA; n=114) or 1 g of intravenous TXA (IV TXA; n=114). The primary outcome of interest was total blood loss (TBL) intra-operatively and up to 48 hours postoperatively. Secondary outcomes included a hemoglobin concentration decrease, D-Dimer levels on days 1 and 3, ...

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