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Intra-Articular Botulinum Toxin A for Knee Osteoarthritis

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Ace Report Cover
March 2023

Intra-Articular Botulinum Toxin A for Knee Osteoarthritis

Vol: 303| Issue: 3| Number:25| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Efficacy and Safety of Intra-Articular Botulinum Toxin A Injection for Knee Osteoarthritis: A Systematic Review, Meta-Analysis, and Meta-Regression of Clinical Trials.

JB JS Open Access. 2023 Jan 20;8(1):e22.00121.

Contributing Authors:
YD Ismiarto GT Prasetiyo

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Synopsis

Six randomized controlled trials containing a total of 446 patients with knee osteoarthritis were included in this systematic review and meta-analysis comparing intra-articular botulinum toxin A injections vs. control (placebo injection; education only). The pooled outcomes of interest were pain on a Visual Analog Scale (VAS) and the Western Ontario and McMaster Universities Osteoarthritis index (...

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