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Vol:255 Issue:3 Number:8 ISSN#:2564-2537
ACE Report #14707
Ace Report Cover Osteoarthritis

Efficacy of Intra-articular Hyaluronic Acid Injections for Knee OA by Molecular Weight

How to Cite

OrthoEvidence. Efficacy of Intra-articular Hyaluronic Acid Injections for Knee OA by Molecular Weight. ACE Report. 2022;255(3):8. Available from:

Study Type:Therapy
OE Level Evidence:N/A
Journal Level of Evidence:N/A

High molecular weight intraarticular hyaluronic acid for the treatment of knee osteoarthritis: a network meta-analysis

BMC Musculoskelet Disord. 2022 01-Jun;():. 10.1186/s12891-020-03729-w

Contributing Authors:
CD Hummer F Angst W Ngai C Whittington SS Yoon L Duarte C Manitt E Schemitsch

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14 randomized controlled trials with a total of 2796 knee osteoarthritis patients were included in this network meta-analysis comparing high molecular weight hyaluronic acid injection, low molecular weight hyaluronic acid injection, intra-articular corticosteroid injection, other FDA-approved conservative therapies, and intra-articular placebo injection. The outcome of interest was pooled pain sco...

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