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Volume:39 Issue:1 Number:1 ISSN#:2563-5476
Meta-analysis
ACE Report #13595
Ace Report Cover Osteoarthritis

Improved Knee Joint Structure but Limited Symptom Alleviation with Sprifermin Injections for Knee OA


How to Cite

OrthoEvidence. Improved Knee Joint Structure but Limited Symptom Alleviation with Sprifermin Injections for Knee OA. ACE Report. 2021;39(1):1. Available from: https://myorthoevidence.com/AceReport/Report/13595

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Efficacy and safety of sprifermin injection for knee osteoarthritis treatment: a meta-analysis

Arthritis Res Ther. 2021 Apr 9;23(1): 107.

Contributing Authors: N Zeng XY Chen ZP Yan JT Li T Liao GX Ni

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Synopsis

Eight randomized controlled trials containing a total of 2671 patients suffering from symptomatic knee osteoarthritis (OA) were included in this meta-analysis comparing injections of sprifermin to placebo. Pooled outcomes of interest include the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total score and its subscores (i.e., pain, function, and stiffness), changes in car...

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