Loading...
Visit our Evidence-Based Covid-19 Website and Stay Up to Date with the latest Research.
Volume:20 Issue:1 Number:4 ISSN#:2563-5476
RCT
ACE Report #13409
Ace Report Cover General Orthopaedics

No Clinical Benefit of LY-CoV555 Antibodies Plus Remdesivir in Hospitalized COVID-19 Patients


How to Cite

OrthoEvidence. No Clinical Benefit of LY-CoV555 Antibodies Plus Remdesivir in Hospitalized COVID-19 Patients. ACE Report. 2021;20(1):4. Available from: https://myorthoevidene.com/AceReport/Report/13409

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19

N Engl J Med. 2021 Mar 11;384(10): 905-914.

Contributing Authors: Group ACTIV-3/TICO LY-CoV555 Study JD Lundgren B Grund CE Barkauskas TL Holland RL Gottlieb U Sandkovsky SM Brown KU Knowlton WH Self DC Files MK Jain T Benfield ME Bowdish BG Leshnower JV Baker JU Jensen EM Gardner AA Ginde ES Harris IS Johansen N Markowitz MA Matthay L √òstergaard CC Chang VJ Davey A Goodman ES Higgs DD Murray TA Murray R Paredes MKB Parmar AN Phillips C Reilly S Sharma RL Dewar M Teitelbaum D Wentworth H Cao P Klekotka AG Babiker AC Gelijns VL Kan MN Polizzotto BT Thompson HC Lane JD Neaton

Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here

Synopsis

Three hundred and fourteen hospitalized patients with COVID-19 were randomized to receive a single intravenous infusion of LY-CoV555 antibody therapy (n=163) or placebo (n=151) for the improvement of recovery and reduction of adverse events. The primary outcomes of interest was sustained recovery (discharged home and remaining at home for at lest 14 days) and a composite safety outcome of death, s...

To view the full report, start your 30-day free trial today

No credit card required

JOIN Forgot Password?

Not sure if you want to join OrthoEvidence?

Access this report without an Account.

Success, an email containing a link to access this report has been sent to your inbox.

CME Image

Continuing Medical Education Credits

You could be earning 0.5 CME credits for each report you read.

LEARN MORE