Sixty-four office employees working at least 20 hours in the office were randomized to receive 36 weeks of ergonomic intervention (adjustment of workstation to improve posture and comfort; n=32) or no intervention (control; n=32) for the improvement of pain. Outcomes of interest included pain intensity in the neck, shoulders, upper back, elbow, lower back, hand/wrist, hip/thigh, knee, and foot/ankle. Outcomes were assessed at 12, 24, and 36 weeks follow-up. Results revealed a significant difference in favour of the ergonomic group compared to the control group for pain in the neck, shoulder, upper back, and hand/wrist (p<0.05 for all). However, in the rate of pain improvement from baseline, no statistically significant differences were observed between the two groups in all regions (p>0.05 for all).