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RCT
ACE Report #11735
Ace Report Cover Trauma

Three doses of 15mg/kg IV TXA reduces blood loss vs. placebo in trochanteric fracture surgery


Study Type:Randomized Trial
OE Level Evidence:1
Journal Level of Evidence:N/A

Efficacy and safety of perioperative tranexamic acid in elderly patients undergoing trochanteric fracture surgery: a randomised controlled trial

Hong Kong Med J. 2019 Apr;25(2):120-126.

Contributing Authors: M Li X Zhu F Chen Z Jiang

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Synopsis

176 patients with trochanteric fractures and scheduled for surgical treatment were randomized to receive 3 doses of intravenous tranexamic acid or placebo (normal saline). Outcomes of interest included peri-operative, obivous and hidden blood loss, post-operative hemoglobin levels, proportion of patients who received red blood cell transfusion, number of transfused red blood cell units per person,...

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