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RCT
ACE Report #11707
Ace Report Cover Arthroplasty

Only analgesic difference between early vs late intraoperative periarticular injection found in PACU


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:1

Early stage periarticular injection during total knee arthroplasty may provide a better postoperative pain relief than late-stage periarticular injection: a randomized-controlled trial

Knee Surg Sports Traumatol Arthrosc. 2019 Apr;27(4):1124-1131. doi: 10.1007/s00167-018-5140-y

Contributing Authors: N Hirasawa S Tsukada K Kurosaka M Nishino T Maeda A Iida

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Synopsis

105 patients scheduled for total knee arthroplasty were randomized to superficial periarticular injection performed either early in the procedure (after exposure of the fascial layer) or late in the procedure (following implant cementation). The primary outcome of interest was pain at rest score from immediately after surgery to 48 hours postoperatively. Results on the primary outcome demonstrated...

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