Use of Tranexamic Acid for Adverse Events Post Posterior Fusion in Patients With Scoliosis .
Evaluation of the use of tranexamic acid in the postoperative period in patients with scoliosis undergoing posterior fusion.
Neurosurg Rev . 2024 Aug 10;47(1):416.Twenty-eight patients with scoliosis (21 idiopathic, 7 other etiologies) were randomized to receive tranexamic acid intraoperatively and postoperatively (n=14) or intraoperatively only (n=14). The primary outcome was postoperative blood loss measured through drain output. Secondary outcomes included transfusion requirements, length of hospital stay, and incidence of adverse effects. Outcomes were assessed during the immediate postoperative period. Overall, the study revealed no statistically significant differences between the two groups in blood loss, transfusion requirements, or hospital stay duration. The findings suggest that the postoperative use of TXA does not significantly improve outcomes compared to intraoperative use alone.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
