40 patients with unilateral clavicular fractures were randomized to receive a brachial plexus block plus either an ultrasound-guided superficial cervical fascia block (n=20) or an ultrasound-guided superficial cervical plexus block (n=20). The primary outcomes of interest were the time to perform nerve block, onset time of the block, sensory block grade, and effective analgesia time. Secondary outcomes of interest included duration of surgery, heart rate (HR), systolic and diastolic blood pressure (SBP & DBP, respectively), and the incidence of adverse events. The time to perform the nerve block, onset time, block effect, and effective analgesia time were significantly better in the superficial fascia block group compared to the superficial plexus block group. Heart rate was significantly lower in the fascia block group at the time of anesthesia induction with HR, SBP, and DBP presenting similar outcomes at all other time points between the two groups.