Treatment of Chronic Neck Pain with Transcranial Direct Current Stimulation: A Single-Blinded Randomized Clinical Trial.
OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2025;13(21):36 Biomedicines . 2025 Jul 17;13(7):1746.What this means for my practice?
tDCS and TENS both reduced pain and disability over 3 months; tDCS additionally improved mechanical pain thresholds and right cervical rotation more than TENS. Clinically, tDCS is a feasible central neuromodulation option to pair with neck-care programs when heightened pain sensitivity is a concern. Limitations include small sample size, single-blind design with likely perceptible allocation, and potential baseline imbalances, tempering generalizability.
Study Summary
Thirty patients with chronic nonspecific neck pain were randomized to receive transcranial direct current stimulation (tDCS)(n=15) or transcutaneous electrical nerve stimulation (TENS) (n=15) across ten sessions over four weeks. The primary outcome was pain intensity (NPRS). Secondary outcomes included disability (NDI), cervical ROM, and PPT, assessed at baseline, post-treatment, one month, and three months. Overall, the results revealed both groups improved significantly over time for NPRS, NDI, ROM, and PPT; however, between-group effects favored tDCS for all PPT sites and for right cervical rotation. In short, tDCS was comparable to TENS for pain and disability but yielded superior mechanical pain sensitivity and selective ROM gains, suggesting a modest advantage of central neuromodulation on hyperalgesia.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
Are you affiliated with one of our partner associations?
Click here to gain complimentary access as part your association member benefits!