Treatment of Early Hip Osteoarthritis: Ultrasound-Guided Platelet Rich Plasma versus Hyaluronic Acid Injections in a Randomized Clinical Trial

研究概要

Eighty patients with symptomatic hip osteoarthritis (OA) were randomized into receiving intra-articular injections of platelet-rich plasma (PRP) or hyaluronic acid (HA). The primary outcome included pain as measured by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) sub-scale for pain and Visual Analogue Score (VAS) for pain. The secondary outcomes measuring the WOMAC subscale for stiffness and function, as well as the Harris Hip Score for function. All outcomes were measured at baseline, and follow-up time periods of 6 and 12 months. Results demonstrated that VAS, WOMAC, and Harris Hip Score all improved significantly from baseline at 6 months and 12 months post-treatment for both treatment arms. Limitations included a lack of comparison between the PRP and HA treatment groups for measuring the greatest effect. Thus, future research is needed to compare these pain and functional outcomes between PRP and HA intra-articular injections for hip OA.