Tranexamic Acid Use in Arthroscopic Rotator Cuff Repair in Older Adults .
Tranexamic acid use in arthroscopic rotator cuff repair: a systematic review and meta-analysis of randomized controlled trials.
JSES Int . 2024 Apr 6;8(5):995-1003.A total of 510 patients with rotator cuff pathology were randomized to receive tranexamic acid (TXA) (n=261) or no TXA (n=249). The primary outcomes of interest were visual clarity during surgery, postoperative pain, and operative time. Secondary outcomes included shoulder swelling. Outcomes were assessed up to one year. Overall, the results revealed that TXA significantly reduced operative time and postoperative pain on day 1. However, the reduction in pain did not reach clinical significance, and there was no effect on shoulder swelling. The impact of TXA on visual clarity was inconclusive. These findings suggest TXA has potential benefits in surgical efficiency but limited clinical significance in pain and swelling outcomes.
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