Total disc replacement is an effective treatment for bi-level degenerative disc disease .
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Prospective, randomized, multicenter food and drug administration investigational device exemption study of the ProDisc-L total disc replacement compared with circumferential arthrodesis for the treatment of two-level lumbar degenerative disc disease
J Bone Joint Surg Am. 2011 Apr 20;93(8):705-15. Epub 2011 Mar 11.237 patients were randomized to undergo total disc arthroplasty or circumferential arthrodesis. Despite the relatively short duration of follow-up, the two-level lumbar disc arthroplasty has been found to be an effective alternative to arthrodesis and offered clinical advantages in terms of pain relief and functional recovery.
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