Seventy patients (84 feet) scheduled for forefoot surgery were randomized to receive wound closure via a topical skin adhesive (n=42 feet) or nylon suturing (n=42 feet). The primary outcome of interest was a wound evaluation on the Hollander Wound Evaluation Scale (HWES). Secondary outcomes of interest included pain, time to final layer closure, dressing change time, and patient satisfaction. Pain and wound evaluation were assessed at 2 weeks post-operation, and complications and satisfaction were assessed at 6 weeks post-operation. As per HWES scores, wound edge separation and inflammation were significantly more likely in the topical skin adhesive group. Also, the time to final layer closure was significantly longer in the topical skin adhesive group compared to the suture. However, significantly lower pain and shorter dressing change time were observed in the topical skin adhesive group.