Topical capsaicin for osteoarthritis pain .
Efficacy and safety of topical capsaicin in the treatment of osteoarthritis pain: A systematic review and meta-analysis.
Phytother Res. 2024 01-Jul;():. 10.1002/ptr.8223Eight double-blind randomized controlled trials involving 498 patients with osteoarthritis were included in this systematic review and meta-analysis comparing topical capsaicin to placebo. Pooled outcomes of interest included pain intensity, physician's global evaluation, joint stiffness, and adverse effects. Capsaicin significantly reduced pain intensity but was associated with a higher incidence of burning sensation at the application site.
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